VIRAL VECTOR QUALITY CONTROL
Advancing viral vector development with quality and precision.
Your trusted partner for comprehensive quality control, testing, and compliance solutions in viral vector production.
It all starts with quality.
At Avid, we understand that quality control is the cornerstone of viral vector production. Working in our state-of-the-art facility, our experts ensure that every batch meets the highest standards of safety, efficacy, and compliance.
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General Capabilities
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Laboratories Engineered for Excellence
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Cutting-Edge Instrumentation
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Comprehensive Viral Vector Testing
Delivering reliable, phase-appropriate quality control solutions to ensure product quality and regulatory compliance at every stage of development.
- Raw material release
- In-process testing
- Lot release testing (both DS and DP)
- Stability testing
- Stability program design
- Stability program management
- Stability trending and reporting
- COA generation
- Method lifecycle maintenance and monitoring
Our specialized labs are designed to meet the unique demands of viral vector testing, combining advanced technology with optimized workflows to ensure reliable, compliant results every time.
- Dedicated cell-based suites
- Dedicated three-room PCR suites
- DNA-free work zone
- DNA zone
- Amplification zone
- Full-pressure cascade to ensure room cleanliness
- 6,000+ ft² dedicated QC space
- Access-controlled cold-storage devices
- 2-8°C
- -20°C
- -80°C
- Cryo freezer for QC cell banks
Laboratories are equipped with the latest in analytical instrumentation, which is also duplicated in our Analytical Development labs, ensuring seamless tech transfer, efficient process scale-up, critical quality attributes and characterization of viral vector products. All instruments are fully qualified per USP <1058> including an assessment of 21 CFR Part 11 and EudraLex Annex 11 principles. A subset of instruments are listed below.
- Biorad QX200 ddPCR system
- Thermo QuantStudio 7
- Molecular Devices ID3 and ID5 plate readers
- Millipore Oasis for Bioburden
- Veolia Eclipse and TOC instruments
- Malvern ZetaSizer Ultra Red for particle size and DLS analysis
- Waters UPLC instruments
- Repligen SoloVPE
- Advanced Instruments Osmometer
Our extensive testing capabilities cover all viral vectors Avid is capable of producing including AAV, Lentivirus, HSV, and others. All Avid QC assays are qualified and/or validated prior to introduction into the GMP QC laboratory and cover critical quality parameters and safety parameters ensuring safe and effective viral vector products.
- Residual impurities by ELISA
- Residual impurities by qPCR (or ddPCR)
- Impurity/purity analysis by HPLC
- Particle analysis by DLS
- Vector genome titer by ddPCR
- Vector purity/identity by electrophoresis
- Endotoxin
- Bioburden
- Cell-based TCID 50
- Cell-based potency
General Capabilities
Delivering reliable, phase-appropriate quality control solutions to ensure product quality and regulatory compliance at every stage of development.
- Raw material release
- In-process testing
- Lot release testing (both DS and DP)
- Stability testing
- Stability program design
- Stability program management
- Stability trending and reporting
- COA generation
- Method lifecycle maintenance and monitoring
Laboratories Engineered for Excellence
Our specialized labs are designed to meet the unique demands of viral vector testing, combining advanced technology with optimized workflows to ensure reliable, compliant results every time.
- Dedicated cell-based suites
- Dedicated three-room PCR suites
- DNA-free work zone
- DNA zone
- Amplification zone
- Full-pressure cascade to ensure room cleanliness
- 6,000+ ft² dedicated QC space
- Access-controlled cold-storage devices
- 2-8°C
- -20°C
- -80°C
- Cryo freezer for QC cell banks
Cutting-Edge Instrumentation
Laboratories are equipped with the latest in analytical instrumentation, which is also duplicated in our Analytical Development labs, ensuring seamless tech transfer, efficient process scale-up, critical quality attributes and characterization of viral vector products. All instruments are fully qualified per USP <1058> including an assessment of 21 CFR Part 11 and EudraLex Annex 11 principles. A subset of instruments are listed below.
- Biorad QX200 ddPCR system
- Thermo QuantStudio 7
- Molecular Devices ID3 and ID5 plate readers
- Millipore Oasis for Bioburden
- Veolia Eclipse and TOC instruments
- Malvern ZetaSizer Ultra Red for particle size and DLS analysis
- Waters UPLC instruments
- Repligen SoloVPE
- Advanced Instruments Osmometer
Comprehensive Viral Vector Testing
Our extensive testing capabilities cover all viral vectors Avid is capable of producing including AAV, Lentivirus, HSV, and others. All Avid QC assays are qualified and/or validated prior to introduction into the GMP QC laboratory and cover critical quality parameters and safety parameters ensuring safe and effective viral vector products.
- Residual impurities by ELISA
- Residual impurities by qPCR (or ddPCR)
- Impurity/purity analysis by HPLC
- Particle analysis by DLS
- Vector genome titer by ddPCR
- Vector purity/identity by electrophoresis
- Endotoxin
- Bioburden
- Cell-based TCID 50
- Cell-based potency
Explore our quality control labs virtually.
Explore our quality control labs virtually.
Ready to optimize your process?
Biologics Quality and Regulatory Compliance
Ready to optimize your process?
Biologics Quality and Regulatory Compliance
WHY AVID?
Your life’s work is in good hands.
Our experts are fully committed to your success, advocating for you and helping to minimize risk.